Pediatric Patients For treatment and prophylaxis of mycobacterial infections in pediatric patients, the recommended dose is 7
Matzke
New York, NY: McGraw-Hill and Lexicomp: Dosing recommendations for individual drugs can be found in Drug Prescribing in Renal Failure: Dosing Guidelines for Adults
nifedipine
, up to 250 mg once daily, or 250 mg twice daily in more severe infections
o Clarithromycin is contraindicated in patients with severe hepatic failure in combination with renal impairment
3 DOSAGE FORMS AND STRENGTHS
4
What Are Side Effects of Biaxin? Biaxin may cause serious side effects including: severe stomach pain, View clarithromycin information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding and directions for administration
Decrease clarithromycin dose by 50%
3 mg qod-qd; ACUTE GOUT TX: avoid combo if already receiving colchicine for gout prophylaxis For oral dosage forms (suspension and tablets): For bacterial infections: Adults—250 to 500 milligrams (mg) every 12 hours for 7 to 14 days
IV: 250-500 mg every 12 hours; 10 : Oral: 250-500 mg every 12 hours
Extended-release Tablets: Severe renal dysfunction (CrCl less than 30 mL/min The renal clearance of clarithromycin is, however, relatively independent of the dose size and approximates the normal glomerular filtration rate
When moderate or severe renal impairment and concomitant atazanavir or ritonavir: reduce clarithromycin dose by ½ (CrCl Renal damage can alter clearance of active drug metabolites, potentially causing accumulation
2
250 mg once daily, or 250 mg twice daily in more severe infections
The structural modifications made to erythromycin significantly changed the spectrum of Clarithromycin is a macrolide antibiotic
By disrupting The renal clearance of clarithromycin is, however, relatively independent of the dose size and approximates the normal glomerular filtration rate
This medicine is available only with your doctor's prescription
No dose adjustment necessary in normal renal function
For example, doctors reduce the dose of clarithromycin to 50% of the usual INDICATIONS AND RESTRICTIONS
As modified-release tab: 500 mg once daily, may be increased to 1,000 Cephalexin is an antibiotic approved by the U
Management: If concurrent use cannot be avoided, reduce talazoparib dose to 0
Duration of therapy: 10 to 14 days
No clear recommendations, but adjustment probably not necessary (<1% renal elimination) Pyrazinamide Adult 20-25 mg/kg PO q24h (Round to 500mg tablet) 40 to 55 kg: 1,000 mg once daily 56 to 75 kg: 1,500 mg once daily CrCl <30 or HD: 25-35 mg/kg three times weekly
Known/suspected renal dysfunction: Frequent monitoring recommended
It is crucial to follow the prescribed pediatric dosing instructions and complete the full course of treatment to ensure effective treatment outcomes in children
See WARNINGS AND PRECAUTIONS, Special Populations, Geriatrics
For oral dosage forms (suspension and tablets): Adults—250 to 500 milligrams (mg) every 12 hours for 7 to 14 days
1990;18(4):441-446
CrCl >50 mL/min
Azithromycin, clarithromycin, and erythromycin are commonly used to treat infections like pneumonia, sinusitis, pharyngitis, and tonsillitis
Potential increased exposure to sildenafil The recommended dosages of BIAXIN Filmtab and BIAXIN XL Filmtab for the treatment of mild to moderate infections in adults are listed in Table 1
Avoid or Use Alternate Drug
Leg ulcer infection By mouth using immediate-release medicines Adult 500 mg twice daily for 7 days
• Adults: BIAXIN 250 mg or 500 mg every 12 hours for 7±14 days; BIAXIN XL 1 gram every 24 hours for 7±14 days (2
Dosage Adjustment Due to Drug Interactions 2
Biaxin: Dosing, contraindications, side effects, and pill pictures - epocrates online Formulary Classes Allergy/Cold/ENT Anesthesia/Pain Management Asthma/Pulmonary
General Renal Dosing Guidelines and a specialized list of renal medication dosing - simple renal dosing
BIAXIN Filmtab (clarithromycin tablets, USP) and BIAXIN Granules (clarithromycin for oral suspension, USP) are indicated for the treatment of mild to
Duration of therapy: 10 to 14 days
Like other macrolides, it then penetrates bacteria cell wall and reversibly binds to domain V of the 23S ribosomal RNA of the 50S subunit of the bacterial ribosome, blocking translocation clarithromycin + colchicine CV EVENT RISK REDUCTION: contraindicated; GOUT or FMF: contraindicated in pts w/ renal or hepatic impairment; otherwise, use alternative or decr
AGGRENOX® (aspirin/extended-release dipyridamole)
7 Dosage Adjustment Due to Drug Interactions 2
The renal clearance of clarithromycin is, however, relatively independent of the dose size and approximates the normal glomerular filtration rate
View clarithromycin information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding and directions for administration
Keflex is a brand name for cephalexin, which belongs to the class of antibiotics called cephalosporins
DOSING FOR GLOMERULAR FILTRATION OF 50-80
However, this medicine will not work for colds, flu, or other virus infections
Known/suspected renal dysfunction: Frequent monitoring recommended
Includes dosages for Bacteremia, Osteomyelitis, Nasal Carriage of Staphylococcus aureus and more; plus renal, liver and dialysis adjustments
An additional 18 days of treatment with omeprazole 20 mg orally once a day is recommended for patients with an ulcer at
The renal clearance of clarithromycin is, however, relatively independent of the dose size and approximates the normal glomerular filtration rate
Immediate-release: 250-500 mg PO q12hr; Extended-release: 1 g PO q24hr; clarithromycin
, ketoconazole, itraconazole, or ritonavir)
Dosage of Clarithromycin: Adult and pediatric dosages: Oral suspension